Eucalyptus Oil

Eucalyptus-oil-bannerAustralian Fever tree is what Eucalyptus is lovingly called as, for its therapeutic values of treating fever and respiratory infections.

As one among the most universally used essential oils, Eucalyptus grants excellent relaxing effect on the mind and relieves excruciating pain in the body as well. With more than 700 varieties of Eucalyptus, the most preferred essential oil of Eucalyptus is extracted from the aromatic leaves of the Eucalyptus globulus tree by steam distillation.

Eucalyptus is known with different names in Sanskrit like Tailapatra, Sugandhapatra and Tailaparna. This tree belongs to the Ayurvedic family lavang kul. It is popularly known in India as ‘Nilgiri taila’ as the most aromatic and healing variety grows in Nilgiris hills in south India.

Ayurvedic preparations make use of Eucalyptus oil for the treatment of tuberculosis, bronchitis, cold, cough, asthma, sinusitis, fever, throat infections and certain other respiratory ailments along with mental fatigue, sluggishness, rheumatism, kidney infections, malaria, neuritis, dandruff, acne, insect bites, herpes simplex and muscular problems.

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Historical uses and importance of Eucalyptus oil:

Indigenous to Australia, Eucalyptus oil is the instant home remedy for everything ranging from headache to muscular pain and this tree is widely spread across India, New Zealand and Australia.

Initially, this oil was used in the native topical ointments in primordial Aboriginal medicines for treating severe wounds, sinus congestion, fungal infections and cough. Now this oil is widely used in all facets including industrial, medicinal and perfumery.

Historical references state that it was Captain James Cook with Daniel Solander and Joseph Banks who found various species of Eucalyptus in Endeavour River, Northern Queensland, and Botany Bay in 1770. Until this time none of the collected Eucalyptus species E. gummifera and E. platyphylla were named and it was named only in 1777 when the Eucalyptus variety found in Bruny Island, Tasmania was taken to the British Museum in London.

The French Botanist L’Heritier named it as Eucalyptus obliqua, where all the species of the Eucalyptus family share a common feature of having oblique leaves, which indicates the leaves that have leaf blades of unequal length and do not meet up the petiole in the same situate.

Eucalyptus is a famous food for the koala bears and an extensive source of food for wildlife in many countries across the globe. Australians used Eucalyptus leaves in preparing tea or infusions for treating fever, sinus congestion, cold and rheumatic pain. This oil was used in the English hospitals for cleaning urinary catheters in the 19th century.

The export of Eucalyptus oil ruled the global market in 1870 and various Surgeons during 1880s used Eucalyptus oil at the time of surgery as an antiseptic. The curative benefits of Eucalyptus oil then quickly spread to other alternative and complementary medicinal practices like Greco-European and the Traditional Chinese Medicine.

Chemical constituents or Gas Chromatography Report (GC) for Eucalyptus oil:

According to the Gas chromatography report, Eucalyptus oil constitutes of 11 chemical components that contribute to its distinctive fragrance, remedial properties and quality. Eucalyptus oil is enriched with about 79% of 1,8-Cineole constituent.

The major chemical components are listed and linked below for your reference:

The major constituent that contributes to the healing property of Eucalyptus essential oil is eucalyptol (promising antiseptic), which is another name for cineole. It also contains flavonoids (antioxidants that are plant-based), tannins (aids in reducing inflammation) and other volatile oils.

The table below on the Gas Chromatography report talks about the principal chemical constituents and its role in granting the therapeutic and other attributes to Eucalyptus oil.

Eucalyptus-oilRemedial properties of Eucalyptus oil:

These components are responsible for the remedial properties of Eucalyptus oil including antioxidant, antiseptic, anti-inflammatory, expectorant, decongestant, mucolytic, mental stimulant, regenerative, diuretic, diaphoretic, antispasmodic, germicidal, deodorant, alterative, anti-diabetic, disinfectant and insect repellent.

Ayurvedic health benefits of Eucalyptus essential oil:

Every human being is born with all physical and mental faculties in palpable order and all that he/she needs to do is to understand the ways of using them perfectly to lead a serene life. This understanding of life is known as ‘Ayurveda’ and the very word means ‘knowledge of life’ (Ayur-life and Veda-knowledge).

This traditional wisdom has its name etched in the history before 5,000 years and is said to be in existence before 1500 B.C. The principles of Ayurveda have been documented in the Atharvaveda, one among the 4 major Vedas (sacred books) of the Hindu Mythology. Nearly 114 poems in this Vedic literature depict the causes, effects and the remedies of various diseases of mankind.

Ayurvedic system strongly believes that everything on earth is a part of nature and is made up of the five vital elements of nature including fire, water, earth, space and air. Earth is said to represent bones and muscles, fire stands for the biological reaction and metabolism of the body, air aids in breathing, water is the blood and space is the soul or spirit that lives within.

The philosophy of Ayurveda states that every individual is made up of a unique individual constitution comprising of three vital biological energies known as doshas. These vital energies are nothing but a representation of the five vital elements of nature.

According to Ayurveda, sickness is a symbol that the human body is in disharmony with nature and there is imbalance of any one or all of the three doshas.

Ayurveda says that disease is an opportunity to know the imbalances of the system. It believes in identifying the root cause of an illness instead of treating the symptoms alone.

Ayurvedic remedies vary from individual to individual even for the same medical condition as it trusts that every individual is a unique creation and the treatment for their illnesses should also be unique.

The major Ayurvedic remedies are essential oils (the life-force of plants), herbs, Abhyanga (the art of Ayurvedic massaging), yoga, meditation, prayers and following an Ayurvedic routine. These remedies are prescribed in such a way that they treat the imbalances of doshas and help to live in harmony with Mother Nature.

Eucalyptus oil is known for increasing pitta dosha and pacifying kapha and vata dosha with its unique medicinal, warm and camphoraceous to lemony aroma.

The Ayurvedic health benefits of Eucalyptus oil are:

Eucalyptus-oil-broucher-new11. Excellent lung cleanser that alleviates respiratory problems:

The oil of Eucalyptus has been held-high for more than thousands of years for its natural potent of treating fever, respiratory problems and lung ailments. Light Miller claims Eucalyptus as “one of the three best oils for any respiratory tract problem because the component eucalyptol is mucolytic (it relaxes the flow of mucous) and it excretes the eucalyptol out through the lung surface.”

Adding 2 drops of Eucalyptus oil in steam inhalation instills a relaxing effect on the mucous membranes, cleans the nasal passages, expands the blood vessels and permits more oxygen intake by the lungs, thus assisting trouble-free breathing and cleansing of lungs.

This oil have been used since the traditional times in the treatment of sinusitis, bronchitis, nasal and chest congestion, cold, sore throat, asthma, tuberculosis, runny nose and throat infections.

A study on ‘Immune-modifying and antimicrobial effects of Eucalyptus oil and simple inhalation devices’ by Sadlon AE, Lamson DW published in 2010 Alternative Medicine says that, “Surprisingly, there are also immune-stimulatory, antioxidant, and spasmolytic effects. Of the white blood cells, monocytes and macrophages are most affected, especially with increased phagocytic activity. Application by either vapor inhalation or oral route provides benefit for both purulent and non-purulent respiratory problems.”

Eucalyptus oil has excellent decongestant, expectorant, antimicrobial, anti-inflammatory, antiviral and antibacterial properties that make its use vital in many cold rubs, ointments and other oral preparations for respiratory problems.

The study on Eucalyptus oil extracted from the aromatic Eucalyptus tree of the Nilgiri hills, India by the Medical Department, Government of Madras, India has proved that Eucalyptus oil works as an effective expectorant and relaxes phlegm and mucous deposits in the nasal and respiratory passages.

The presence of phenolic compounds, the plant based antioxidants in Eucalyptus oil helps in fighting against respiratory infections by strengthening the immune system during flu, cough, cold and other illnesses. 2 drops of Eucalyptus oil added to cold compress or applied to foot soles helps in reducing fever. You can also add 2 drops of this oil in ointments or rubs and massage it gently on the chest, throat and back for relieving nasal and chest congestion.

2. Relieves pain effectively:

Whenever headache hits us badly, the first thing that comes to most of our minds is Eucalyptus oil. Yes! This powerful pain-relieving oil has analgesic and natural pain relieving qualities.

A recent double blind study have illustrated that Eucalyptus oil and Peppermint oil applied together on temples and forehead proved better in relieving headache better than pharmaceutical aspirin and acetaminophen.

A 1991 study on the ‘Effects of a topically applied counter-irritant (Eucalyptamint) on cutaneous blood flow and on skin and muscle temperatures. A placebo-controlled study.’ By the University of California Irvine Medical Center suggested that “Eucalyptamint, produced significant physiologic responses that may be beneficial for pain relief and/or useful to athletes as a passive form of warm-up.”

Eucalyptus essential oil alleviates pain by spreading its warming effect on the skin, causing numbness on the painful parts and relieves pain quickly. Its anti-inflammatory, analgesic and diuretic properties assists in relieving muscular pain, rheumatic pain, joint aches, arthritic pain, lumbago, stiff muscles, fibrositis, nerve pain and migraine pain.

A 2013 study on ‘Effect of Eucalyptus Oil Inhalation on Pain and Inflammatory Responses after Total Knee Replacement: A Randomized Clinical Trial’ by the Department of Basic Nursing Science, School of Nursing, Korea University have stated that, “Eucalyptus oil inhalation was effective in reducing patient’s subjective pain and blood pressure after surgery. These findings suggest that the inhalation of eucalyptus oil might be a valuable nursing intervention for pain relief after TKR (Total Knee Replacement).”

Massaging the affected parts with 2 drops of Eucalyptus oil mixed with 1 drop of Peppermint oil and 2 ml of coconut oil can help in lessening pain and reducing swelling by eliminating the excess water deposits, salt , uric acid or other toxic substances causing inflammation in case or arthritis or rheumatism. You can also add 3 drops of Eucalyptus oil in warm bathing water and go for a re-energizing bath to calm your aching muscles and nerves.

3. Keeps away oral problems:

The essential oil of Eucalyptus oil is rich in 1,8-cineole (eucalyptol), which is an effective antiseptic that eradicates bacteria and other harmful microbes that can cause bad breath and other oral problems.

It is also said that the antibacterial effect of this oil assists in fighting against periodontopathic bacteria and cariogenic bacteria, which is responsible for causing decay of tooth.

A 2008 study on ‘Effect of eucalyptus extract chewing gum on periodontal health: a double-masked, randomized trial.’ By the Department of Preventive Dentistry, Osaka, Japan witnessed the effectiveness of Eucalyptus oil by stating that “Eucalyptus extract chewing gum had a significant effect on Plaque accumulation (PLA), gingival index (GI), bleeding on probing (BOP), periodontal probing depth (PD). The use of eucalyptus extract chewing gum may promote periodontal health.”

The best way to used Eucalyptus oil for combating germs and bacteria causing oral problems is to add 1 drop of this oil in a cup of water and use it as a gargle twice a day. This is the major cause for the use of Eucalyptus formula in various mouthwashes and other oral cleansers to fight cavity, gingivitis, halitosis and plaque.

4. Mitigates mental exhaustion:

Eucalyptus essential oil instills a cooling effect on the mind and helps repair and rejuvenate negative feelings and subtle emotions. Numerous studies have proved that this oil has been effective in alleviating stress, mental fatigue, depression due to illness, lack of concentration, mental aversion and other strong emotions.

1 drop of Eucalyptus oil mixed with 1 drop of Lemon oil and added to your vaporizer or diffuser can grant mental clarity quotes the book ‘Ayurveda and Aromatherapy’ by Bryan Miller and Light Miller. You can also add 2 drops of this oil in your bathing water in the morning or before going to bed to calm your nerves, soothe your senses and leave you invigorated and balanced.

You can add 10 drops of Eucalyptus oil to your 2.5 ounce spray bottle and spray it in your work station to assist in clarity of thoughts, improved concentration, logical thinking, increased intellectual power and focused approached even towards the most complex task of the day.

5. Heals wounds and infections quickly:

The effective germicidal and antiseptic properties of Eucalyptus oil promotes quicker healing of burns, infectious wounds, abrasions, skin ulcers, cuts and dry itchy patches. Eucalyptus oil has antimicrobial and germicidal effects that curb the growth of perilous bacteria like Staphylococcus aureus and E.coli and a 2004 research on ‘A study of the antimicrobial activity of oil of Eucalyptus’ proves this effectiveness.

Apply 2 drops of Eucalyptus oil mixed with 1 ml of jojoba oil and apply on the wounds, acne, candida, blisters, boils (it is safe on chicken pox boils also), shingles, herpes simplex and other skin infections for visible results.

It is also said that Eucalyptus oil was effectively used for treating childhood infectious diseases like typhoid, cholera, mumps, measles and scarlet fever. You can add 2 drops of this oil warm bathing water or mix it with 1 ml of coconut and massage it gently on foot soles to reduce fever and other infectious health conditions.

6. Promising insect repellent:

Eucalyptus essential oil is a potent insecticide and pesticide. It is a renowned formula in many insect repellents in the market and the oil of Eucalyptus mixed with lemon oil is said to keep away ticks.

The Australian Aborigines used Eucalyptus oil as an effective insect repellent to protect them from mosquitoes, ticks and fleas. Using this oil can assist in preventing critical diseases like malaria, Lyme disease, West Nile virus and Rocky mountain spotted fever.

Add 2 drops of Eucalyptus oil to 2 ml of coconut oil and gently massage it on your scalp to get rid of lice and dandruff (anti-fungal). Mix 2 drops of Eucalyptus oil with 1 ml of olive oil and apply it on insect bites to get rid of rashes, reduce itching and redness of the skin. You can also apply this mix before going to bed to protect yourself from mosquitoes. 2 to 3 drops of this oil added to your air freshener or diffuser can give you a bug-free sleep at night.

Other health benefits:

Eucalyptus oil is also effective in treating other disorders like bladder infections, skin blemishes, sluggishness, fatigue, emotional pressure, dysentery, loss of appetite, laryngitis, intestinal worms, wounds and loss of appetite.

Disclaimer:

This article is restricted to educational use only and is not for substituting any prescribed medication or professional medical advice. Speak with your Ayurvedic healthcare expert before choosing the appropriate essential oils for your specific health condition and unique individual constitution.

Always use essential oils for topical use in a diluted manner as certified and organic essential oils are highly concentrated extracts and may cause allergic conditions when used on the skin directly. Eucalyptus oil is safe as it comes under GRAS (generally regarded as safe) oils but never use it internally.

The MSDS (Material Safety Data Sheet) of Eucalyptus oil is readily available for your enhanced safety and better usage.

Gas Chromatography Report (GC analysis) of Eucalyptus oil.

Thought for the day:

Knowing trees, I understand the meaning of patience. Knowing grass, I can appreciate persistence.     

-Hal Borland

Suggested Reading:

  1. The Power of Eucalyptus for Health & Healing by Jack Malloy
  2. How to Use Eucalyptus Essential Oil (Aromatherapy) by Miriam Kinai
  3. Eucalyptus Leaf Oils Use Chemistry Distillation and Marketing by Boland
  4. HEALING POWERS OF EUCALYPTUS Pure Essential Oil – Respiratory Healer (The Aromatherapy Professional: Healing with Essential Oils) by KG Stiles
  5. Eucalyptus: The Genus Eucalyptus (Medicinal and Aromatic Plants – Industrial Profiles) From CRC Press

Reference Links:

  1. Eucalyptus by Wikipedia
  2. Eucalyptus By The University of Maryland Medical Center
  3. The Lung Cleansing Benefits of Eucalyptus by Global Healing Center
  4. Effect of eucalyptus extract chewing gum on periodontal health: a double-masked, randomized trial.’ By the Department of Preventive Dentistry, Osaka, Japan published in Pubmed
  5. Effect of Eucalyptus Oil Inhalation on Pain and Inflammatory Responses after Total Knee Replacement: A Randomized Clinical Trial’ by the Department of Basic Nursing Science, School of Nursing, Korea University published in Evidence-Based Complementary and Alternative Medicine Volume 2013


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Kappor Katcheri Oil

Kapoor-katcheri-bannerKnown as Shati in Ayurveda, Kappor Katcheri herb and the essential oil extracted from the rhizomes of this plant through steam distillation process has been in use traditionally for treating respiratory problems (like bronchitis and asthma), wounds, fever, ulcers, cough, indigestion, hiccough, inflammation and certain other eye problems.

Kappor Katcheri is a Hindi name and is scientifically called as Hedychium spicatum. It is a limb of the Ginger family Zingiberaceae. It is a small hardy ginger with bright and large white and orange flowers and is indigenous to the subtropical Himalayan regions in India at an altitude of 1000 to 3000 m.

Purchase Kappor Katcheri Oil – Retail – 4 oz – CLICK HERE

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Historical uses of Kappor Katcheri:

The aromatic and herbaceous rhizomes of Kappor Katcheri herb has been used in various traditions for treating numerous health conditions. The Ayurvedic healing system use this herb for curing respiratory problems, poor blood circulation, indigestion, wounds and inflammation. It was used as a natural remedy for treating diarrhea, vomiting, snake bite, fever and inflammation in the Traditional Chinese Medicine.

Kappor Katcheri was used in the Tibetan medicine for its heating potency and acrid taste and was also used as an effective insect repellant. Known as Sanna in Japan, the rhizomes of this plant are also used in preparing Attar Ekangi in India.

Therapeutic properties and chemical constituents of Kappor Katcheri oil:

The major chemical constituents present in Kappor Katcheri essential oil are limonene, cineole, terpinene, linalool, p-cymene, terpeneol and phellandrene. These components contribute to its remedial properties like antioxidant, antifungal, hypoglycemic, in vitro pediculicidal, spasmolytic, cytotoxic, tranquilizer, CNS depressant, febrifuge, anti-inflammatory, anthelmintic, analgesic, antispasmodic, hypotensive, vasodilator and antimicrobial.

Ayurvedic health benefits of Kappor Katcheri oil:

Ayurveda is the oldest of all healing methodologies on earth dating back to more than 5,000 years. This ancient science aims at educating humanity about the natural remedies in treating illnesses, ways to prevent sickness and pass towards healthy aging.

The Ayurvedic Physicians like Charaka, known as the Father of Medicine and Sushruta called as the Father of Surgery have enlisted almost all the possible natural remedies for a wide range of illnesses in the Ayurvedic encyclopedias well-known as Charaka Samhita and Sushruta Samhita respectively.

These ancient treasures talk about all types of healing herbs on earth and their effectiveness in curing various illnesses. According to these books, Kappor Katcheri is an excellent remedy for treating respiratory illnesses like asthma and bronchitis.

Along with herbs, Ayurvedic treatments include the use of essential oils, practicing healthy and balanced diet, Ayurvedic routine, meditation, physical exercises and yoga. Every human being is a unique part of nature according to Ayurveda and it suggests that the treatment should also be unique according to an individual’s constitution even for the same illness.

This constitution is made up of three vital bio-energies known as doshas that is vata, pitta and kapha. Every one of us will have a predominance of any one of these doshas that determines our health, personality and behavioral attributes.

Balance between these doshas indicates good health and imbalance between these doshas symbolize illness. Ayurvedic medications are prescribed in such a way that it treats dosha imbalances. Kappor Katcheri essential oil lessens pitta and kapha dosha and aggravates vata dosha.

The Ayurvedic health benefits of Kappor Katcheri oil are:

Kappor-katcheri-broucher1. Excellent support for respiratory problems:

The powdered rhizomes of Hedychium spicatum has been used clinically and in the traditional healing system for treating respiratory problems like respiratory inflammatory conditions including asthma, bronchospasms and bronchitis. It has also been proved effective in treating cough, cold, headache, fever, sinusitis and certain other breathing difficulties.

A 2012 study on ‘Pharmacological evaluation of extracts of Hedychium spicatum (Ham-ex-Smith) rhizome by Shivani Ghildiyal, Manish K. Gautam,Vinod K. Joshi, and Raj K. Goel’ states that the rhizomes of Hedychium spicatum has been reported to contain antiasthmatic, anti-inflammatory, vasodilator, hypotensive, spasmolytic and hypoglycemic properties.

Based upon various animal studies on mouse and Guinea pigs, this study concluded that the rhizomes of H. spicatum has anti-histaminic, bronchodilator, analgesic, anti-inflammatory activities that are essential to soothe pain, inflammation, asthma, bronchoconstriction and other respiratory problems.

Heat 2 drops of Kappor Katcheri oil with 1 ml of coconut oil and apply it on the throat, chest and back or add 2 drops of this oil in steam inhalation for relieving from congestion, bronchial spasms, asthma, cough and breathing difficulties.

The spicy and camphoraceous aroma of this oil along with its chemical constituents like terpinene and cineole have been proved as powerful analgesic and anti-inflammatory agents that assist in treating respiratory problems since the ancient times.

2. Natural antimicrobial aid:

The rhizomes and the essential oil of Kappor Katcheri herb are said to exhibit inhibitory activity against numerous Gram positive and Gram negative bacteria including Staphylococcus aureus and against few other fungal cultures according to a 2006 study on ‘Antimicrobial activity of Hedychium spicatum.’

Bacteria, fungi and certain other micro organisms are responsible for numerous health problems. These organisms damage the cells and weaken the immune system while making the body susceptible for diseases.

As a natural antimicrobial agent, Kappor Katcheri essential oil comes to your rescue when there’s a need to keep micro organisms at bay. Add 2 drops of this oil in warm bathing water to prevent and protect you from microbes. You can add 1 drop of Kappor Katcheri oil with 10 drops of coconut oil and apply it on wounds, ringworm, acne, cuts, athlete’s foot, nail infections and other skin allergies for visible results.

3. Scavenges free radicals:

Kappor Katcheri oil has antioxidant properties that assist in scavenging free radicals, which are known as reactive molecules engaged in numerous physiological processes and human illnesses like arthritis, cancer, ischemia, alcoholism, ageing, liver injuries and certain other toxin induced reactions.

A 2011 study on the ‘Antioxidant activity of Hedychium spicatum Buch.- Ham. Rhizomes’ by T Sravani and Padmaa M Paarakh, Department of Pharmacognosy, The Oxford College of Pharmacy, India published in the Indian Journal of Natural Products and Resources demonstrated that the rhizomes of Hedychium spicatum plant possess strong antioxidant activity.

You can use the essential oil extracted from these rhizomes as bath oil by adding 2 drops of Kappor Katcheri oil to your bath tub or by using it in massage by blending 4 drops of Kappor Katcheri oil with 2 ml of sesame oil for combating the effects of free radicals.

4. Alleviates pain and inflammation:

Kappor Katcheri oil possesses analgesic, anti-inflammatory, spasmolytic and tranquilizer effects that aid in treating pain, inflammation, arthritis and rheumatic problems. Blend 2 drops of Kappor Katcheri oil with 1 ml of sesame oil and massage on the affected area or add it in hot or cold compress to relieve pain, inflammation, spasms and irritation. When applied to the painful parts this blend will cause numbness and reduce your pain gradually.

5. Guards the entire system:

Apart from these major uses, Kappor Katcheri oil is known for its effectiveness in treating gastric ulcer, fever, intestinal infections, abdominal pain, blood purification, eye diseases and hypertension.

Disclaimer:

This article is only for the purpose of education and is not meant to replace any prescription medicine or professional advice of a medical expert. Do not use essential oils internally. Always use essential oils in a diluted form as pure and organic essential oils are highly concentrated liquids and can cause harm if used directly on skin.

It is advisable to do a patch test on your skin before using essential oils to test its suitability to your skin condition. Consult your Ayurvedic practitioner regarding the use of best essential oils for your unique health condition and individual constitution.

Thought for the day:

Every flower is a soul blossoming in nature. -Gerard De Nerval

Suggested Reading:

  1. Identification of Chemical Constituents of Plant Hedychium Spicatum: Methods for Phytochemical analysis and standardization by Alok Pratap Singh
  2. Evaluation of CNS potential of Hedychium spicatum: Rhizome Extract by Versha Parcha, Vichitra Kaushik, Arun Kumar
  3. Hardy Gingers: Including Hedychium, Roscoea, and Zingiber by T. M. E. Branney
  4. Paradise Found: Growing Tropicals in Your Own Backyard by Norman Winter

Reference Links:

  1. Pharmacological evaluation of extracts of Hedychium spicatum (Ham-ex-Smith) rhizome by Shivani Ghildiyal, Manish K. Gautam,Vinod K. Joshi, and Raj K. Goel published in PubMed
  2. Antioxidant activity of Hedychium spicatum Buch.- Ham. Rhizomes by T Sravani and Padmaa M Paarakh, Department of Pharmacognosy, The Oxford College of Pharmacy, India published in the Indian Journal of Natural Products and Resources
  3. Hedychium spicatum – Buch.-Ham by Plants for a Future
  4. Antimicrobial activity of Hedychium spicatum by G.S. Bhist, A.K. Awasthi, T.N. Dhole, Department of Microbiology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India published in ScienceDirect