gamma-Eudesmol

Gamma-eudesmol is a sesquiterpene present mainly in the wood oil of the plant species Callitris collumellaris, Callitris intratropica, Callitris glaucophyla, which are found in Australia.

It is also present in the essential oil of Juniperus virginiana, Cajuput oil, Eucalyptus oil, Guava fruit oil etc.,

The molecular formula for gamma-eudesmol is C15H26O. It is also known by various other names such as (+)-gamma-eudesmol, Uncineol, Machilol, Selinenol and so on.

Attributes of Gamma-eudesmol:

Gamma-eudesmol owns a medium waxy smell.

Therapeutic attributes of gamma-eudesmol:

The primary curative properties of gamma-eudesmol are as follows:

Cytotoxicity:

The study titled ‘Eudesmol isomers induce caspase-mediated apoptosis in human hepatocellular carcinoma HepG2 cells’ was conducted to investigate the cytotoxic effect of eudesmol isomers, namely alpha-eudesmol, beta-eudesmol and gamma-eudesmol against cancerous cells in liver.

It was found that the three eudesmol isomers exhibited potential cytotoxic activity against cancerous cells in liver by reducing the proliferation and causing the death of tumor cells by caspase-mediated apoptosis.

According to the study ‘In vitro and in vivo antitumor effects of the essential oil from the leaves of Guatteria friesiana’,  it was found that the antitumor effects exhibited by the essential oil from the leaves of Guatteria friesiana is contributed by the eudesmol isomers, alpha-eudesmol, beta-eudesmol and gamma-eudesmol. Further, they also show signs of significant cytotoxic activity against tumor cells.

Reference Links:

  1. Gamma-eudesmol by PubChem
  2. Eudesmol isomers induce caspase-mediated apoptosis in human hepatocellular carcinoma HepG2 cells
  3. In vitro and in vivo antitumor effects of the essential oil from the leaves of Guatteria friesiana

Ayurveda and Turmeric Essential Oil: The Natural Bond

You can seldom find an Indian kitchen without this noble herb named ‘Turmeric’, used since 4000 years in the ancient healing system known as Ayurveda. The power of this herb is being realized by the contemporary researchers and innumerable research studies prove its efficiency, fighting for its stand in healing even the most complicated of the diseases. Each and every part of the turmeric plant is beneficial in its own ways and the essential oil is extracted from the rhizomes or the roots of this plant and that is why most of the times, Turmeric essential oil is favorably called as Turmeric root essential oil. Whenever and wherever you talk about or think about Ayurveda, you can never neglect the essence and health values imparted by this grand herb known as ‘Kanchani’ in Sanskrit meaning ‘The Golden Goddess’.

Healing properties of ‘versatile’ herb Turmeric: Turmeric herb is scientifically known as Curcuma Longa. The essential oil extracted from  the roots or bulbs of  this Indian Saffron plant by steam distillation process is said to have anti-inflammatory, anti-bacterial, analgesic, anti-oxidant, anti-spasmodic, antiseptic, diuretic, anti-allergic, digestive, vulnerary, carminative, astringent, cardiovascular, cholagogue, anti-tumor, appetizer, stimulant and alterative properties proven to be the best natural cure for the most problematical human illnesses like cancer, HIV/AIDS, Alzheimer’s disease, urinary tract infections, amenorrhea, hemorrhoids, gallstones, sexually transmitted diseases (STD) like Genital Herpes, Hepatitis-C etc, liver problems and even the most obscure skin disorders. Ayurveda suggests the use of turmeric in daily cooking for its priceless medicinal benefits.

Ayurvedic health benefits of Turmeric essential oil: Ayurveda has proudly named Turmeric as an ‘All-Purpose Cleanser’, insisting on the benefits of this herb in purifying the body from internal and external disorders. This energizing herb is meant to support the imbalance of Kapha body type (who are generally fat, obese and with a hefty body) with its warming properties and that is why Turmeric is used as an effective remedy in numerous natural weight-loss treatments. It also helps in resuming the function of pitta and vata body types also.

Nature’s shield against cancer: Cancer is hard to think and difficult to digest and I have personally felt the pain of losing my near ones to this deadly disease, being ignorant of the curative values granted by Ayurveda few years back. Turmeric has been used in numerous Ayurvedic treatments to help fight against cancer as it is said to restrain the development of fresh blood vessels in tumors and holds its growth. An accepted research in 2011 has witnessed that Turmeric essential oil has the capacity to fight against the free radicals in the body and act as excellent antioxidant, antinociceptive and anti-inflammatory agents. Ayurveda’s uses of Turmeric oil as an effective tool for preventing cancer has again been proved by this research which says that Turmeric essential oil increases the level of Glutathione-S-transferase (GST) and augment carcinogen detoxification in the human body and effectively function as a perfect cancer-preventing force.

Brilliantly assists the digestive system: Along with imparting irresistible aroma and flavor to the food, turmeric supports the function of the digestive system. The safety prescribing authority of herbs in Germany known as the German Commission E has allegedly approved the use of Turmeric in treating digestive disorders. It stimulates the mucous element in the gastric juices and aids in curing irritable bowel syndrome, ulcers, constipation and other chronic digestive disorders. Turmeric essential oil strengthens digestion and eliminates the toxins that are stored in the gastrointestinal tract.

Pampers the skin perfectly: Turmeric is the beauty secret of Queens since the prehistoric period. Ayurveda suggests the use of Turmeric daily as it protects the skin from harmful bodies and gives a flawless fair complexion. You might have come across the use of Turmeric essential oil in innumerable skin care products in the market for it is celebrated to treat wounds, eczema, wrinkles, pigmentation of skin, pimples, acne, psoriasis, cuts, burns and other skin infections.

Other health conditions: According to Ayurveda, turmeric is said to reduce Kapha (mucous secretion) and hence it is used an as effective aid in treating respiratory problems like asthma, bronchitis, accumulation of phlegm, common cold, cough, flu etc. It improves blood circulation and helps in treating female health problems like amenorrhea, dysmennorhea, uterine tumors, endometriosis and cysts. It protects the liver, treats diabetes, kidney pain, colitis, food poisoning, headache, vascular dysfunction, blood pressure, inflammation, swelling and reduces excess cholesterol.

How to use Turmeric essential oil: This powerful essential oil can be diluted with carrier oils and used as a topical application or for a relaxing Ayurvedic massage. Few drops of oil can be added to potpourris, vaporizers, candles or diffusers for combating germs in the air and protecting the environment naturally. It can also be added to your bath tub for an aromatic, healing, stimulating and energizing bath. Turmeric essential oil is generally ingested for its antioxidant and anti-inflammatory properties but it is strictly advised to consult an expert Ayurvedic Practitioner before using this oil internally and if you are pregnant or getting ready for a child.

All that glitters is not gold’ is a popular adage. With the bright golden color, Turmeric in the Ayurvedic world can be remembered by saying ‘All that glitters is Turmeric’ (rightly called as the Golden Goddess).

Thought for the day♥

He who has health has hope; and he who has hope, has everything.

                                                                                    -Thomas Carlyle

Suggested reading:

  1. Turmeric: The Ayurvedic Spice of Life by Prashanti DeJager MS
  2. Curcumin: The 21st Century Cure: Prevent and Reverse: cancer, depression and dementia, digestive disorders, diabetes, pain and arthritis, heart disease and more by Jan McBarron M.D.
  3. Turmeric and the Healing Curcuminoids by Muhammed Majeed, Vladimir Badmaev, Frank Murray

Reference Links:

  1. Turmeric: ‘The Golden Goddess’ by California College of Ayurveda
  2. Turmeric by University of Maryland Medical Center
  3. An evaluation of antioxidant, anti-inflammatory, and antinociceptive activities of essential oil from Curcuma longa. L by PubMed
  4. Uses of Turmeric in Ayurveda by IndiaNetzone

Isomenthone

Isomenthone is an organic compound present in the essential oils of Bergamot, Corn mint, Geranium, Lemongrass, Mangrove bark, Peppermint, Agathosma crenulata, Pennyroyal and Petitgrain.

The chemical formula for isomenthone is C10H18O. It is also known by the other names such as L-Isomenthone, cis-Menthone, (-)-Isomenthone, (1) – Isomenthone and so on.

Attributes of Isomenthone:

Isomenthone is a colorless liquid, which is clear in nature. It has a cool and mentholic minty aroma.

Therapeutic attributes of Isomenthone:

The major remedial values of Isomenthone are:

Antioxidant activity:

According to the study ‘Antimicrobial and antioxidant activities of three Mentha species essential oils’, it was found that menthone and Isomenthone present in Mentha longifolis L. and Mentha piperita potentially exhibit free radical scavenging activity.

In another study ‘In-vitro Antioxidant Activity and GC/MS Studies on the Leaves of Mentha piperita (Lamiaceae) from Morocco’, it was brought into light that Isomenthone present in the essential oil of Mentha piperita exhibit potential free radical scavenging activity and it is one of the constituents that contribute to the antioxidant activity of the oil.

In the book, “Herbs and Natural Supplements, Volume 2, An evidence-Based Guide” it is mentioned that Peppermint and its constituents, Menthone and Isomenthone exhibit antioxidant activity.

Antiviral effect:

Isomenthone possess antiviral effect against Herpes Simplex type-1(HSV-1), which is evident from the study ‘Antimicrobial and antiviral effects of essential oils from selected Umbelliferae and Labiatae plants and individual essential oil components’.

This study is focused on the antibacterial and antiviral activity exhibited by the essential oils from selected plants of Umbelliferae and Labiatae family and their constituents.

Isomenthone was one of the constituents present in the essential oils of the plants under study and it was tested for its antiviral effect against Herpes Simplex type-1 virus. It was found that Isomenthone exhibited antiviral activity against Herpes simplex type-1 virus with the values of cytopathogenic effect ranging between .8 and 0.025 μg mL-1.

Protection of human dermal fibroblasts:

Dermal fibroblasts are the cells present in the dermis layer of the skin and its function is to generate connective tissue and aid in fast recovery of the skin during injury. A study titled ‘Isomenthone protects human dermal fibroblasts from TNF-α-induced death possibly by preventing activation of JNK and p38 MAPK’ was carried out to evaluate the protective effects of Isomenthone against tumor necrosis factor-α (TNF-α) and its role in human dermal fibroblasts.

It was found that Isomenthone protects dermal fibroblasts by suppressing the TNF-α mediated reduction in cell viability and reduced the increase in apoptosis and also hindered JNK and p38 MAPK pathways.

Reference Links:

  1. Isomenthone by PubChem
  2. Antimicrobial and antioxidant activities of three Mentha species essential oils
  3. In-vitro Antioxidant Activity and GC/MSStudies on the Leaves of Mentha piperita (Lamiaceae) from Morocco
  4. Antimicrobial and antiviral effects of essential oils from selected Umbelliferae and Labiatae plants and individual essential oil components
  5. Isomenthone protects human dermal fibroblasts from TNF-α-induced death possibly by preventing activation of JNK and p38 MAPK